Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SO_0013Metal-dependent phosphohydrolase. (347 aa)    
Predicted Functional Partners:
parE
DNA topoisomerase IV B subunit ParE; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
  
 0.791
SO_1254
Signal transduction superfamily protein with modified HD-GYP domain.
  
    0.780
SO_2538
Two component signal transduction system response regulator.
  
     0.731
SO_3337
Signal transduction protein with HDOD/GAF domains.
 
     0.717
flgI
Flagellar P-ring protein FlgI; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.631
fliA
RNA polymerase sigma-28 factor for flagellar operon FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
     0.558
flgH
Flagellar L-ring protein FlgH; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.538
flgD
Flagellar hook assembly protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
    0.478
flgG
Flagellar component of cell-distal portion of basal-body rod FlgG; Belongs to the flagella basal body rod proteins family.
 
    0.462
fliM
Flagellar motor switching and energizing component FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
    0.456
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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