Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hutUUrocanate hydratase HutU; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)    
Predicted Functional Partners:
hutI
Imidazolonepropionase HutI; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 0.999
hutH
Histidine ammonia-lyase HutH; Belongs to the PAL/histidase family.
 
 0.999
SO_3057
Phenylalanine/histidine ammonia-lyase family protein.
 
 
 0.994
SO_4374
Phenylalanine/tyrosine ammonia-lyase.
 
 0.991
SO_3299
Phenylalanine/histidine ammonia-lyase family protein.
 
 
 0.965
hutC
Transcriptional repressor of histidine utilization genes HutC.
 
  
 0.946
urdA
FAD-dependent oxidoreductase; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate [...]
     
 0.902
hutD
Putative histidine degradation protein HutD.
 
  
 0.857
hisB
Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
     
 0.846
hisC
Histidinol-phosphate aminotransferase HisC; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.720
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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