| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_3047 | ychN | SO_3047 | SO_0325 | Protein of unknown function DUF1097. | Protein YchN. | 0.586 |
| SO_3047 | yedE | SO_3047 | SO_0108 | Protein of unknown function DUF1097. | Membrane protein of unknown function DUF395 YedE. | 0.595 |
| SO_3047 | yedF | SO_3047 | SO_0109 | Protein of unknown function DUF1097. | SirA family protein YedF; Belongs to the sulfur carrier protein TusA family. | 0.562 |
| SO_3108 | cysG | SO_3108 | SO_3728 | Bifunctional 13-dimethyluroporphyrinogen III dehydrogenase/siroheme ferrochelatase. | uroporphyrin-III C-methyltransferase CysG; Belongs to the precorrin methyltransferase family. | 0.999 |
| SO_3108 | yedF | SO_3108 | SO_0109 | Bifunctional 13-dimethyluroporphyrinogen III dehydrogenase/siroheme ferrochelatase. | SirA family protein YedF; Belongs to the sulfur carrier protein TusA family. | 0.525 |
| cysG | SO_3108 | SO_3728 | SO_3108 | uroporphyrin-III C-methyltransferase CysG; Belongs to the precorrin methyltransferase family. | Bifunctional 13-dimethyluroporphyrinogen III dehydrogenase/siroheme ferrochelatase. | 0.999 |
| cysG | yedF | SO_3728 | SO_0109 | uroporphyrin-III C-methyltransferase CysG; Belongs to the precorrin methyltransferase family. | SirA family protein YedF; Belongs to the sulfur carrier protein TusA family. | 0.525 |
| fdhD | iscS | SO_0107 | SO_2264 | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.404 |
| fdhD | selA | SO_0107 | SO_0105 | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | L-seryl-tRNA selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | 0.734 |
| fdhD | selB | SO_0107 | SO_0106 | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Selenocysteine-specific translation elongation factor SelB. | 0.712 |
| fdhD | yedE | SO_0107 | SO_0108 | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Membrane protein of unknown function DUF395 YedE. | 0.569 |
| fdhD | yedF | SO_0107 | SO_0109 | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | SirA family protein YedF; Belongs to the sulfur carrier protein TusA family. | 0.582 |
| iscS | fdhD | SO_2264 | SO_0107 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.404 |
| iscS | yedF | SO_2264 | SO_0109 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | SirA family protein YedF; Belongs to the sulfur carrier protein TusA family. | 0.809 |
| selA | fdhD | SO_0105 | SO_0107 | L-seryl-tRNA selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.734 |
| selA | selB | SO_0105 | SO_0106 | L-seryl-tRNA selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | Selenocysteine-specific translation elongation factor SelB. | 0.998 |
| selA | yedE | SO_0105 | SO_0108 | L-seryl-tRNA selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | Membrane protein of unknown function DUF395 YedE. | 0.643 |
| selA | yedF | SO_0105 | SO_0109 | L-seryl-tRNA selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | SirA family protein YedF; Belongs to the sulfur carrier protein TusA family. | 0.598 |
| selB | fdhD | SO_0106 | SO_0107 | Selenocysteine-specific translation elongation factor SelB. | Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.712 |
| selB | selA | SO_0106 | SO_0105 | Selenocysteine-specific translation elongation factor SelB. | L-seryl-tRNA selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | 0.998 |