STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmEABC-type heme export system chaperone component CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity); Belongs to the CcmE/CycJ family. (161 aa)    
Predicted Functional Partners:
ccmC
ABC-type heme export system permease component 2 CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmB
ABC-type heme export system permease component 1 CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 
 0.995
ccmD
ABC-type heme export system CcmE-interacting component CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
 
 0.992
ccmA
ABC-type heme export system ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
 
 0.992
ccmF
Cytochrome c synthetase cytochrome b containing quinol-haem oxidoreductase subunit CcmF.
 
 
 0.986
ccmH
Cytochrome c synthetase subunit CcmH; Possible subunit of a heme lyase.
 
  
 0.961
ccmG
Cytochrome c maturation system membrane anchored thioredoxin CcmG.
 
  
 0.959
sirE
Cytochrome c maturation system haem lyase subunit SirE.
 
 
 0.919
ccmI
Apo-cytochrome c chaperone CcmI.
 
  
 0.893
sirF
Cytochrome c maturation system haem lyase subunit SirF; Possible subunit of a heme lyase.
 
  
 0.829
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.