| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0690 | dam | SO_0690 | SO_0289 | Mu phage DNA adenine methylase Dam family. | N6-adenine DNA methyltransferase Dam. | 0.927 |
| SO_0690 | purL | SO_0690 | SO_3287 | Mu phage DNA adenine methylase Dam family. | Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.664 |
| SO_0690 | rplI | SO_0690 | SO_3927 | Mu phage DNA adenine methylase Dam family. | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 0.571 |
| aroB | aroK | SO_0287 | SO_0286 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.999 |
| aroB | dam | SO_0287 | SO_0289 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | N6-adenine DNA methyltransferase Dam. | 0.710 |
| aroB | damX | SO_0287 | SO_0288 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Cell division protein DamX. | 0.870 |
| aroB | trpS | SO_0287 | SO_0294 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.421 |
| aroK | aroB | SO_0286 | SO_0287 | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.999 |
| aroK | dam | SO_0286 | SO_0289 | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | N6-adenine DNA methyltransferase Dam. | 0.628 |
| aroK | damX | SO_0286 | SO_0288 | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Cell division protein DamX. | 0.805 |
| aroK | trpS | SO_0286 | SO_0294 | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.454 |
| dam | SO_0690 | SO_0289 | SO_0690 | N6-adenine DNA methyltransferase Dam. | Mu phage DNA adenine methylase Dam family. | 0.927 |
| dam | aroB | SO_0289 | SO_0287 | N6-adenine DNA methyltransferase Dam. | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.710 |
| dam | aroK | SO_0289 | SO_0286 | N6-adenine DNA methyltransferase Dam. | Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.628 |
| dam | damX | SO_0289 | SO_0288 | N6-adenine DNA methyltransferase Dam. | Cell division protein DamX. | 0.664 |
| dam | gph | SO_0289 | SO_0293 | N6-adenine DNA methyltransferase Dam. | 2-phosphoglycolate phosphatase Gph; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | 0.660 |
| dam | metJ | SO_0289 | SO_4057 | N6-adenine DNA methyltransferase Dam. | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.597 |
| dam | mutH | SO_0289 | SO_1330 | N6-adenine DNA methyltransferase Dam. | DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. | 0.755 |
| dam | purL | SO_0289 | SO_3287 | N6-adenine DNA methyltransferase Dam. | Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.664 |
| dam | rplI | SO_0289 | SO_3927 | N6-adenine DNA methyltransferase Dam. | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 0.571 |