STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gph2-phosphoglycolate phosphatase Gph; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (227 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase Rpe; Belongs to the ribulose-phosphate 3-epimerase family.
 
  
 0.997
hprA
NADH-dependent hydroxypyruvate reductase HprA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.902
trpS
tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.875
dam
N6-adenine DNA methyltransferase Dam.
 
  
 0.650
ung
uracil-DNA glycosylase Ung; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
      0.618
cysW
ABC-type sulfate/thiosulfate uptake system permease component 2 CysW.
     
 0.556
cysW-2
ABC-type sulfate/thiosulfate uptakesystem permease component 2 CysW.
     
 0.526
moaA
Molybdenum cofactor biosynthesis protein A MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.499
moaA-2
Tungsten cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.499
nosD
ABC-type copper transport system substrate-binding component NosD.
      
 0.491
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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