STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmhAPhosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (197 aa)    
Predicted Functional Partners:
gmhB
DD-heptose 17-bisphosphate phosphatase GmhB.
  
 0.995
rfaE
Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
   
 0.981
SO_0297
BON domain lipoprotein.
  
    0.865
hisB
Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
  
  
 0.810
tpiA
Triosephosphate isomeraseTpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
  
 0.770
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
   
 
 0.753
waaC
ADP-heptose-LPS heptosyltransferase WaaC.
 
   
 0.737
miaE
tRNA-(MS(2)IO(6)A)-hydroxylase MiaE.
   
  
 0.722
nlpE
Outer membrane lipoprotein NlpE.
   
  
 0.712
SO_0299
Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family.
  
  
 0.666
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.