| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0297 | SO_0299 | SO_0297 | SO_0299 | BON domain lipoprotein. | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | 0.646 |
| SO_0297 | gmhA | SO_0297 | SO_0298 | BON domain lipoprotein. | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.892 |
| SO_0297 | lppC | SO_0297 | SO_0300 | BON domain lipoprotein. | Outer membrane lipoprotein LppC. | 0.683 |
| SO_0299 | SO_0297 | SO_0299 | SO_0297 | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | BON domain lipoprotein. | 0.646 |
| SO_0299 | gmhA | SO_0299 | SO_0298 | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.727 |
| SO_0299 | lppC | SO_0299 | SO_0300 | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | Outer membrane lipoprotein LppC. | 0.849 |
| dnaA | gmhA | SO_0008 | SO_0298 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.768 |
| dnaA | kdsD | SO_0008 | SO_3956 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Arabinose-5-phosphate isomerase KdsD. | 0.628 |
| dnaA | tpiA | SO_0008 | SO_1200 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Triosephosphate isomeraseTpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.483 |
| gmhA | SO_0297 | SO_0298 | SO_0297 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | BON domain lipoprotein. | 0.892 |
| gmhA | SO_0299 | SO_0298 | SO_0299 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | 0.727 |
| gmhA | dnaA | SO_0298 | SO_0008 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.768 |
| gmhA | gmhB | SO_0298 | SO_2851 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | DD-heptose 17-bisphosphate phosphatase GmhB. | 0.997 |
| gmhA | hisB | SO_0298 | SO_2071 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.843 |
| gmhA | kdsD | SO_0298 | SO_3956 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Arabinose-5-phosphate isomerase KdsD. | 0.673 |
| gmhA | lppC | SO_0298 | SO_0300 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Outer membrane lipoprotein LppC. | 0.732 |
| gmhA | rfaE | SO_0298 | SO_3745 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. | 0.998 |
| gmhA | tpiA | SO_0298 | SO_1200 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Triosephosphate isomeraseTpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.770 |
| gmhA | waaC | SO_0298 | SO_4678 | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | ADP-heptose-LPS heptosyltransferase WaaC. | 0.702 |
| gmhB | gmhA | SO_2851 | SO_0298 | DD-heptose 17-bisphosphate phosphatase GmhB. | Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.997 |