| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0299 | lppC | SO_0299 | SO_0300 | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | Outer membrane lipoprotein LppC. | 0.812 |
| SO_0299 | rsmI | SO_0299 | SO_0301 | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | 16S rRNA (cytidine1402-2'-O)-methyltransferase RsmI; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.603 |
| ftsZ | leuS | SO_4215 | SO_1174 | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.703 |
| ftsZ | metG | SO_4215 | SO_2619 | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.549 |
| ftsZ | panB | SO_4215 | SO_0870 | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.468 |
| ftsZ | rsmI | SO_4215 | SO_0301 | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 16S rRNA (cytidine1402-2'-O)-methyltransferase RsmI; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.641 |
| lepA | leuS | SO_1346 | SO_1174 | Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.822 |
| lepA | metG | SO_1346 | SO_2619 | Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.716 |
| lepA | rluC | SO_1346 | SO_2784 | Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 23S rRNA pseudouridine955/2504/2580 synthase RluC; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.669 |
| lepA | rpmF | SO_1346 | SO_2780 | Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 50S ribosomal protein L32 RpmF; Belongs to the bacterial ribosomal protein bL32 family. | 0.980 |
| lepA | rpsU | SO_1346 | SO_1288 | Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 30S ribosomal protein S21 RpsU; Belongs to the bacterial ribosomal protein bS21 family. | 0.968 |
| lepA | rsmI | SO_1346 | SO_0301 | Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 16S rRNA (cytidine1402-2'-O)-methyltransferase RsmI; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.810 |
| leuS | ftsZ | SO_1174 | SO_4215 | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.703 |
| leuS | lepA | SO_1174 | SO_1346 | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.822 |
| leuS | metG | SO_1174 | SO_2619 | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.997 |
| leuS | rluC | SO_1174 | SO_2784 | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | 23S rRNA pseudouridine955/2504/2580 synthase RluC; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.526 |
| leuS | rpmF | SO_1174 | SO_2780 | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | 50S ribosomal protein L32 RpmF; Belongs to the bacterial ribosomal protein bL32 family. | 0.515 |
| leuS | rsmI | SO_1174 | SO_0301 | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. | 16S rRNA (cytidine1402-2'-O)-methyltransferase RsmI; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.787 |
| lppC | SO_0299 | SO_0300 | SO_0299 | Outer membrane lipoprotein LppC. | Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family. | 0.812 |
| lppC | rsmI | SO_0300 | SO_0301 | Outer membrane lipoprotein LppC. | 16S rRNA (cytidine1402-2'-O)-methyltransferase RsmI; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.603 |