| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0369 | SO_0370 | SO_0369 | SO_0370 | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | Inner membrane protein of unknown function DUF606. | 0.468 |
| SO_0369 | SO_0371 | SO_0369 | SO_0371 | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | Membrane protein of unknown function DUF606. | 0.450 |
| SO_0370 | SO_0369 | SO_0370 | SO_0369 | Inner membrane protein of unknown function DUF606. | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | 0.468 |
| SO_0370 | SO_0371 | SO_0370 | SO_0371 | Inner membrane protein of unknown function DUF606. | Membrane protein of unknown function DUF606. | 0.993 |
| SO_0370 | mnmC | SO_0370 | SO_3073 | Inner membrane protein of unknown function DUF606. | Bifunctional 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. | 0.400 |
| SO_0370 | pyrB | SO_0370 | SO_1301 | Inner membrane protein of unknown function DUF606. | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.404 |
| SO_0370 | pyrD | SO_0370 | SO_2592 | Inner membrane protein of unknown function DUF606. | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.537 |
| SO_0370 | pyrE | SO_0370 | SO_4255 | Inner membrane protein of unknown function DUF606. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.568 |
| SO_0370 | pyrF | SO_0370 | SO_2398 | Inner membrane protein of unknown function DUF606. | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.564 |
| SO_0370 | yfiC | SO_0370 | SO_0948 | Inner membrane protein of unknown function DUF606. | tRNA (adenine-N(6)-)-methyltransferase YfiC; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.443 |
| SO_0370 | yjjG | SO_0370 | SO_0372 | Inner membrane protein of unknown function DUF606. | 5' nucleotide phosphatase YjjG. | 0.419 |
| SO_0371 | SO_0369 | SO_0371 | SO_0369 | Membrane protein of unknown function DUF606. | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | 0.450 |
| SO_0371 | SO_0370 | SO_0371 | SO_0370 | Membrane protein of unknown function DUF606. | Inner membrane protein of unknown function DUF606. | 0.993 |
| SO_0371 | pyrB | SO_0371 | SO_1301 | Membrane protein of unknown function DUF606. | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.404 |
| SO_0371 | pyrD | SO_0371 | SO_2592 | Membrane protein of unknown function DUF606. | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.537 |
| SO_0371 | pyrE | SO_0371 | SO_4255 | Membrane protein of unknown function DUF606. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.568 |
| SO_0371 | pyrF | SO_0371 | SO_2398 | Membrane protein of unknown function DUF606. | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.564 |
| SO_0371 | yjjG | SO_0371 | SO_0372 | Membrane protein of unknown function DUF606. | 5' nucleotide phosphatase YjjG. | 0.470 |
| mnmC | SO_0370 | SO_3073 | SO_0370 | Bifunctional 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. | Inner membrane protein of unknown function DUF606. | 0.400 |
| mnmC | yfiC | SO_3073 | SO_0948 | Bifunctional 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. | tRNA (adenine-N(6)-)-methyltransferase YfiC; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.418 |