| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0369 | SO_0370 | SO_0369 | SO_0370 | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | Inner membrane protein of unknown function DUF606. | 0.467 |
| SO_0369 | SO_0371 | SO_0369 | SO_0371 | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | Membrane protein of unknown function DUF606. | 0.456 |
| SO_0370 | SO_0369 | SO_0370 | SO_0369 | Inner membrane protein of unknown function DUF606. | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | 0.467 |
| SO_0370 | SO_0371 | SO_0370 | SO_0371 | Inner membrane protein of unknown function DUF606. | Membrane protein of unknown function DUF606. | 0.993 |
| SO_0370 | pyrD | SO_0370 | SO_2592 | Inner membrane protein of unknown function DUF606. | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.521 |
| SO_0370 | pyrE | SO_0370 | SO_4255 | Inner membrane protein of unknown function DUF606. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.520 |
| SO_0370 | pyrF | SO_0370 | SO_2398 | Inner membrane protein of unknown function DUF606. | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.519 |
| SO_0370 | yjjG | SO_0370 | SO_0372 | Inner membrane protein of unknown function DUF606. | 5' nucleotide phosphatase YjjG. | 0.419 |
| SO_0371 | SO_0369 | SO_0371 | SO_0369 | Membrane protein of unknown function DUF606. | Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family. | 0.456 |
| SO_0371 | SO_0370 | SO_0371 | SO_0370 | Membrane protein of unknown function DUF606. | Inner membrane protein of unknown function DUF606. | 0.993 |
| SO_0371 | pyrD | SO_0371 | SO_2592 | Membrane protein of unknown function DUF606. | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.521 |
| SO_0371 | pyrE | SO_0371 | SO_4255 | Membrane protein of unknown function DUF606. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.520 |
| SO_0371 | pyrF | SO_0371 | SO_2398 | Membrane protein of unknown function DUF606. | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.519 |
| SO_0371 | speC | SO_0371 | SO_4136 | Membrane protein of unknown function DUF606. | Ornithine decarboxylase SpeC; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.442 |
| SO_0371 | yjjG | SO_0371 | SO_0372 | Membrane protein of unknown function DUF606. | 5' nucleotide phosphatase YjjG. | 0.473 |
| pyrD | SO_0370 | SO_2592 | SO_0370 | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Inner membrane protein of unknown function DUF606. | 0.521 |
| pyrD | SO_0371 | SO_2592 | SO_0371 | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Membrane protein of unknown function DUF606. | 0.521 |
| pyrD | pyrE | SO_2592 | SO_4255 | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.999 |
| pyrD | pyrF | SO_2592 | SO_2398 | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.970 |
| pyrE | SO_0370 | SO_4255 | SO_0370 | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Inner membrane protein of unknown function DUF606. | 0.520 |