| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dusB | fis | SO_0394 | SO_0393 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.998 |
| dusB | prmA | SO_0394 | SO_0395 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Ribosomal protein L11 methyltransferase PrmA; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.892 |
| dusB | rimM | SO_0394 | SO_1358 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.618 |
| dusB | rnpA | SO_0394 | SO_0006 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Ribonuclease P protein RnpA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.804 |
| dusB | rpsP | SO_0394 | SO_1357 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 30S ribosomal protein S16 RpsP; Belongs to the bacterial ribosomal protein bS16 family. | 0.623 |
| dusB | rpsT | SO_0394 | SO_3537 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 30S ribosomal protein S20 RpsT; Binds directly to 16S ribosomal RNA. | 0.604 |
| dusB | rpsU | SO_0394 | SO_1288 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 30S ribosomal protein S21 RpsU; Belongs to the bacterial ribosomal protein bS21 family. | 0.661 |
| dusB | suhB | SO_0394 | SO_2260 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Inositol-phosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. | 0.622 |
| dusB | trmD | SO_0394 | SO_1359 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | tRNA (guanine-N1)-methyltransferase TrmD; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.796 |
| dusB | truA | SO_0394 | SO_3068 | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.621 |
| fis | dusB | SO_0393 | SO_0394 | Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.998 |
| fis | prmA | SO_0393 | SO_0395 | Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Ribosomal protein L11 methyltransferase PrmA; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.937 |
| fis | rnpA | SO_0393 | SO_0006 | Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Ribonuclease P protein RnpA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.600 |
| fis | rpsT | SO_0393 | SO_3537 | Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 30S ribosomal protein S20 RpsT; Binds directly to 16S ribosomal RNA. | 0.567 |
| fis | rpsU | SO_0393 | SO_1288 | Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 30S ribosomal protein S21 RpsU; Belongs to the bacterial ribosomal protein bS21 family. | 0.403 |
| prmA | dusB | SO_0395 | SO_0394 | Ribosomal protein L11 methyltransferase PrmA; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.892 |
| prmA | fis | SO_0395 | SO_0393 | Ribosomal protein L11 methyltransferase PrmA; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.937 |
| prmA | rpsU | SO_0395 | SO_1288 | Ribosomal protein L11 methyltransferase PrmA; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 30S ribosomal protein S21 RpsU; Belongs to the bacterial ribosomal protein bS21 family. | 0.452 |
| rimM | dusB | SO_1358 | SO_0394 | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.618 |
| rimM | rnpA | SO_1358 | SO_0006 | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Ribonuclease P protein RnpA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.792 |