Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mutT7,8-dihydro-8-oxoguanine-triphosphatase MutT. (130 aa)    
Predicted Functional Partners:
mutY
Adenine glycosylase MutY; Adenine glycosylase active on G-A mispairs.
  
  
 0.863
uvrD
DNA helicase II UvrD.
     
 0.691
polB
DNA polymerase II PolB.
     
 0.675
apaH
Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
      
 0.670
rnhA
Ribonuclease HI RnhA; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.668
yqcC
tRNA pseudouridine synthase C-associated protein of unknown function DUF446 YqcC.
      
 0.667
yebG
UV induced SOS regulon protein YebG.
      
 0.666
rdgC
Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family.
   
  
 0.665
polA
DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.613
recB
Exodeoxyribonuclease V beta subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination an [...]
     
 0.583
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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