Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadCNicotinate-nucleotide pyrophosphorylase NadC; Belongs to the NadC/ModD family. (293 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase component of quinolinate synthetase NadB; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.999
nadA
Quinolinate synthetase NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
pncC
Nicotinamide deamidase PncC; One of the key enzymes of the pyridine nucleotide cycle which permits cells to recycle the by products of NAD consumption back to NAD. Has no activity on NAD, NADP, nicotinamide or nicotinamide riboside.
    
 0.991
nadD
Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.990
nadV
Nicotinamide phosphoribosyltransferase NadV; Belongs to the NAPRTase family.
   
 
 0.950
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.907
sdhA
Succinate dehydrogenase flavoprotein subunit SdhA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.903
SO_3442
Nucleoside triphosphate pyrophosphohydrolase.
    
  0.902
ushA
Bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA; Belongs to the 5'-nucleotidase family.
     
  0.900
nagD
Haloacid dehalogenase subfamily IIA associated with N-acetylglucosamine degradation NagD.
   
 
  0.900
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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