| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ampC | ampD | SO_2388 | SO_0421 | Class C beta-lactamase AmpC. | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | 0.918 |
| ampC | ampG | SO_2388 | SO_3814 | Class C beta-lactamase AmpC. | GlcNAc-anhMurNAc permease AmpG. | 0.915 |
| ampC | anmK | SO_2388 | SO_1313 | Class C beta-lactamase AmpC. | anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.681 |
| ampC | blaA | SO_2388 | SO_0837 | Class C beta-lactamase AmpC. | Class D carbapenem-hydrolyzing beta-lactamase BlaA. | 0.922 |
| ampC | ftsI | SO_2388 | SO_4225 | Class C beta-lactamase AmpC. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.646 |
| ampC | mpl | SO_2388 | SO_3805 | Class C beta-lactamase AmpC. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase Mpl; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.675 |
| ampC | mrdA | SO_2388 | SO_1168 | Class C beta-lactamase AmpC. | Penicillin-binding protein 2 MrdA; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.468 |
| ampC | nagZ | SO_2388 | SO_2250 | Class C beta-lactamase AmpC. | beta-N-acetylglucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.876 |
| ampD | ampC | SO_0421 | SO_2388 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | Class C beta-lactamase AmpC. | 0.918 |
| ampD | ampE | SO_0421 | SO_0422 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | AmpD signaling modulator AmpE. | 0.587 |
| ampD | ampG | SO_0421 | SO_3814 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | GlcNAc-anhMurNAc permease AmpG. | 0.941 |
| ampD | anmK | SO_0421 | SO_1313 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.894 |
| ampD | blaA | SO_0421 | SO_0837 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | Class D carbapenem-hydrolyzing beta-lactamase BlaA. | 0.788 |
| ampD | ftsI | SO_0421 | SO_4225 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.551 |
| ampD | mpl | SO_0421 | SO_3805 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase Mpl; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.849 |
| ampD | mrdA | SO_0421 | SO_1168 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | Penicillin-binding protein 2 MrdA; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.571 |
| ampD | nadC | SO_0421 | SO_0419 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | Nicotinate-nucleotide pyrophosphorylase NadC; Belongs to the NadC/ModD family. | 0.571 |
| ampD | nagZ | SO_0421 | SO_2250 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | beta-N-acetylglucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.940 |
| ampE | ampD | SO_0422 | SO_0421 | AmpD signaling modulator AmpE. | N-acetyl-anhydromuramyl-L-alanine amidase AmpD. | 0.587 |
| ampE | nadC | SO_0422 | SO_0419 | AmpD signaling modulator AmpE. | Nicotinate-nucleotide pyrophosphorylase NadC; Belongs to the NadC/ModD family. | 0.470 |