Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
aceEPyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)    
Predicted Functional Partners:
aceF
Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
lpdA
Dihydrolipoamide dehydrogenase LpdA.
 
 0.999
pykA
Pyruvate kinase II PykA; Belongs to the pyruvate kinase family.
  
 
 0.938
ppsA
Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.935
pgi
Glucose-6-phosphate isomerase Pgi.
  
 
 0.932
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 
 0.920
sfcA
NAD-dependent malate dehydrogenase (oxaloacetate-decarboxylating) SfcA; Belongs to the malic enzymes family.
    
 0.912
maeB
NADP-dependent malate dehydrogenase (oxaloacetate-decarboxylating) MaeB.
    
 0.912
bkdB
3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB.
 
 
 0.911
dld
Respiratory FAD-dependent D-lactate dehydrogenase Dld.
  
 
 0.909
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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