STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
aceEPyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)    
Predicted Functional Partners:
aceF
Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
lpdA
Dihydrolipoamide dehydrogenase LpdA.
 
 
 0.996
pflB
Pyruvate formate-lyase PflB.
   
 
 0.943
ppsA
Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
 
 0.939
pykA
Pyruvate kinase II PykA; Belongs to the pyruvate kinase family.
  
 
 0.929
sfcA
NAD-dependent malate dehydrogenase (oxaloacetate-decarboxylating) SfcA; Belongs to the malic enzymes family.
    
 0.916
maeB
NADP-dependent malate dehydrogenase (oxaloacetate-decarboxylating) MaeB.
    
 0.916
pgi
Glucose-6-phosphate isomerase Pgi.
  
 
 0.914
ldhA
Fermentative lactate dehydrogenase NADH dependent LdhA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.905
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 
 0.859
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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