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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirASulfite reductase octaheme cytochrome c SirA; Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process. Required for sulfite respiration under anaerobic growth conditions. Does not contribute to nitrite reduction. (708 aa)    
Predicted Functional Partners:
sirI
Cytochrome c maturation system peptidyl-prolyl cis-trans isomerase SirI.
  
  
 0.945
sirD
Menaquinol oxidase SirD.
  
  
 0.782
sirB
Sulfurtransferase SirB.
  
    0.741
ccmI
Apo-cytochrome c chaperone CcmI.
     
 0.666
sirG
Cytochrome c maturation system haem lyase subunit SirG.
  
  
 0.661
SO_0676
Mu phage uncharacterized protein.
   
    0.608
SO_0717
Periplasmic monoheme cytochrome c4.
   
  
 0.535
nrfA
Ammonia-forming nitrite reductase NrfA; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine. Has even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH (By similarity); Belongs to the cytochrome c-552 family.
  
  
 0.521
sseA
Mercaptopyruvate sulfurtransferase SseA.
      
 0.509
nosL
ABC-type copper uptake system periplasmic chaperone component NosL.
     
 0.502
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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