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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirICytochrome c maturation system peptidyl-prolyl cis-trans isomerase SirI. (259 aa)    
Predicted Functional Partners:
sirA
Sulfite reductase octaheme cytochrome c SirA; Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process. Required for sulfite respiration under anaerobic growth conditions. Does not contribute to nitrite reduction.
  
  
 0.945
sirB
Sulfurtransferase SirB.
  
    0.849
sirG
Cytochrome c maturation system haem lyase subunit SirG.
  
  
 0.778
apaH
Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 
 0.721
sirD
Menaquinol oxidase SirD.
 
  
 0.716
htpG
Heat shock chaperone HtpG; Molecular chaperone. Has ATPase activity.
   
 0.664
infA
Translation initiation factor IF-1 InfA; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.605
nosL
ABC-type copper uptake system periplasmic chaperone component NosL.
     
 0.603
nosY
ABC-type copper transport system permease component NosY.
     
 0.594
sirE
Cytochrome c maturation system haem lyase subunit SirE.
   
  
 0.577
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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