STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SO_0519Heavy metal efflux pump MFP component CzcB family. (433 aa)    
Predicted Functional Partners:
SO_0518
Heavy metal efflux pump secretin component CzcC family.
  
 
 0.923
SO_0520
Heavy metal efflux pump permease component CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.911
cusA
Copper/silver efflux pump permease component CusA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  
 0.869
cusB
Copper/silver efflux pump MFP component CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
    0.782
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.588
cusF
Copper efflux pump periplasmic metallochaperone CusF.
 
    0.472
SO_0516
Uncharacterized protein.
  
    0.470
macC
ABC-type macrolide export system secretin component MacC.
  
 
 0.464
tolC
Global secretion system secretin TolC.
  
 
 0.464
SO_4090
ABC-type efflux system secretin component.
  
 
 0.464
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.