| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0544 | SO_0545 | SO_0544 | SO_0545 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | 0.923 |
| SO_0544 | SO_0859 | SO_0544 | SO_0859 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.864 |
| SO_0544 | SO_1055 | SO_0544 | SO_1055 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Diguanylate cyclase with PAS and GAF sensory domains. | 0.789 |
| SO_0544 | SO_3759 | SO_0544 | SO_3759 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Diguanylate cyclase with GAF sensory domain. | 0.928 |
| SO_0544 | SO_4002 | SO_0544 | SO_4002 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.874 |
| SO_0544 | SO_4445 | SO_0544 | SO_4445 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Two component signal transduction system hybrid histidine kinase/response regulator. | 0.806 |
| SO_0544 | SO_4567 | SO_0544 | SO_4567 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Transcriptional regulator AsnC family. | 0.807 |
| SO_0544 | SO_4768 | SO_0544 | SO_4768 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Two component signal transduction system response regulator. | 0.949 |
| SO_0544 | barA | SO_0544 | SO_3457 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.897 |
| SO_0544 | torS | SO_0544 | SO_1230 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.836 |
| SO_0545 | SO_0544 | SO_0545 | SO_0544 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | 0.923 |
| SO_0545 | SO_0859 | SO_0545 | SO_0859 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.957 |
| SO_0545 | SO_1055 | SO_0545 | SO_1055 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Diguanylate cyclase with PAS and GAF sensory domains. | 0.711 |
| SO_0545 | SO_3759 | SO_0545 | SO_3759 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Diguanylate cyclase with GAF sensory domain. | 0.552 |
| SO_0545 | SO_4002 | SO_0545 | SO_4002 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.943 |
| SO_0545 | SO_4445 | SO_0545 | SO_4445 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Two component signal transduction system hybrid histidine kinase/response regulator. | 0.776 |
| SO_0545 | SO_4768 | SO_0545 | SO_4768 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Two component signal transduction system response regulator. | 0.781 |
| SO_0545 | barA | SO_0545 | SO_3457 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.968 |
| SO_0545 | torS | SO_0545 | SO_1230 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.851 |
| SO_0859 | SO_0544 | SO_0859 | SO_0544 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | 0.864 |