| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0544 | SO_0545 | SO_0544 | SO_0545 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | 0.923 |
| SO_0544 | SO_0859 | SO_0544 | SO_0859 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.864 |
| SO_0544 | SO_0860 | SO_0544 | SO_0860 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Two component signal transduction system response regulator with HD domain. | 0.435 |
| SO_0544 | SO_4002 | SO_0544 | SO_4002 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.874 |
| SO_0544 | SO_4003 | SO_0544 | SO_4003 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Metal dependent phosphohydrolase with response regulator receiver modulation. | 0.405 |
| SO_0544 | barA | SO_0544 | SO_3457 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.897 |
| SO_0544 | torS | SO_0544 | SO_1230 | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.836 |
| SO_0545 | SO_0544 | SO_0545 | SO_0544 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | 0.923 |
| SO_0545 | SO_0760 | SO_0545 | SO_0760 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Ammonium transporter channel family protein. | 0.819 |
| SO_0545 | SO_0859 | SO_0545 | SO_0859 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.957 |
| SO_0545 | SO_0860 | SO_0545 | SO_0860 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Two component signal transduction system response regulator with HD domain. | 0.907 |
| SO_0545 | SO_2039 | SO_0545 | SO_2039 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Signalling protein with EAL domain. | 0.822 |
| SO_0545 | SO_4002 | SO_0545 | SO_4002 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.943 |
| SO_0545 | SO_4003 | SO_0545 | SO_4003 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Metal dependent phosphohydrolase with response regulator receiver modulation. | 0.828 |
| SO_0545 | barA | SO_0545 | SO_3457 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.968 |
| SO_0545 | cheY-3 | SO_0545 | SO_2547 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Chemotaxis signal transduction system response regulator CheY. | 0.803 |
| SO_0545 | torS | SO_0545 | SO_1230 | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.851 |
| SO_0760 | SO_0545 | SO_0760 | SO_0545 | Ammonium transporter channel family protein. | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | 0.819 |
| SO_0859 | SO_0544 | SO_0859 | SO_0544 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase with CHASE and PAS sensory domains. | 0.864 |
| SO_0859 | SO_0545 | SO_0859 | SO_0545 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity. | 0.957 |