| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0549 | SO_0859 | SO_0549 | SO_0859 | Two component signal transduction system response regulator. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.978 |
| SO_0549 | SO_4002 | SO_0549 | SO_4002 | Two component signal transduction system response regulator. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.979 |
| SO_0549 | barA | SO_0549 | SO_3457 | Two component signal transduction system response regulator. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.976 |
| SO_0549 | cheA | SO_0549 | SO_2121 | Two component signal transduction system response regulator. | Chemotaxis signal transduction system histidine kinase CheA. | 0.914 |
| SO_0549 | cheA-2 | SO_0549 | SO_3207 | Two component signal transduction system response regulator. | Chemotaxis signal transduction system histidine kinase CheA. | 0.936 |
| SO_0549 | cheC-2 | SO_0549 | SO_2546 | Two component signal transduction system response regulator. | Chemotaxis signal transduction system inhibitor of MCP methylation CheC. | 0.905 |
| SO_0549 | cheX | SO_0549 | SO_3915 | Two component signal transduction system response regulator. | Chemotaxis signal transduction system CheY dephosphorylase CheX. | 0.914 |
| SO_0549 | cheZ | SO_0549 | SO_3208 | Two component signal transduction system response regulator. | Chemotaxis signal transduction system CheY phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). | 0.937 |
| SO_0549 | fliN | SO_0549 | SO_3220 | Two component signal transduction system response regulator. | Flagellar motor switching and energizing component FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. | 0.915 |
| SO_0549 | torS | SO_0549 | SO_1230 | Two component signal transduction system response regulator. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.982 |
| SO_0859 | SO_0549 | SO_0859 | SO_0549 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator. | 0.978 |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.991 |
| SO_0859 | cheA | SO_0859 | SO_2121 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system histidine kinase CheA. | 0.741 |
| SO_0859 | cheA-2 | SO_0859 | SO_3207 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system histidine kinase CheA. | 0.741 |
| SO_0859 | cheX | SO_0859 | SO_3915 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system CheY dephosphorylase CheX. | 0.580 |
| SO_0859 | cheZ | SO_0859 | SO_3208 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system CheY phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). | 0.693 |
| SO_0859 | fliN | SO_0859 | SO_3220 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Flagellar motor switching and energizing component FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. | 0.788 |
| SO_0859 | torS | SO_0859 | SO_1230 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.989 |
| SO_4002 | SO_0549 | SO_4002 | SO_0549 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator. | 0.979 |