STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
znuAABC-type zinc uptake system substrate-binding component ZnuA. (293 aa)    
Predicted Functional Partners:
znuB
ABC-type zinc uptake system permease component ZnuB.
 
 
 0.999
SO_0564
Zinc-regulated TonB-dependent zinc receptor.
 
    0.954
SO_4820
ABC-type zinc uptake system zinc chaperone.
    
  0.952
SO_1502
GTPase involved in metallocenter biosynthesis of metalloproteins COG0523 family.
  
  
 0.773
rpsN
30S ribosomal protein S14 RpsN; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
  
 0.697
rpmB
50S ribosomal protein L28 RpmB; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.679
fur
Transcriptional repressor of iron homeostasis Fur; Belongs to the Fur family.
  
  
 0.520
purL
Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.490
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
     
 0.458
thyA
Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.445
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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