STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SO_0585D-isomer specific 2-hydroxyacid dehydrogenase family protein. (311 aa)    
Predicted Functional Partners:
serC
Bifunctional 3-phosphoserine aminotransferase/phosphohydroxythreonine SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.707
ldhA
Fermentative lactate dehydrogenase NADH dependent LdhA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
     0.678
SO_0586
Membrane protein of unknown function DUF3392.
     
 0.601
yhdE
Maf septum formation family protein YhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
   0.550
thrA
Bifunctional aspartokinase I / homoserine dehydrogenase I ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.534
metL
Bifunctional aspartokinase II/homoserine dehydrogenase methionine-sensitive MetL; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.534
udk
Uridine kinase Udk.
   
  0.530
SO_1652
Hydrolase PHP family.
  
  
 0.525
metH
B12-dependent 5-methyltetrahydrofolate--homocysteine methyltransferase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.461
SO_1815
Histone deacetylase superfamily protein.
 
 
 0.457
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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