STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbsKRibokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (303 aa)    
Predicted Functional Partners:
rpiA
Ribose 5-phosphate isomerase RpiA; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 0.964
rihA
Pyrimidine-specific ribonucleoside hydrolase RihA; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
  
 0.956
tkt
Transketolase Tkt; Belongs to the transketolase family.
  
 0.949
prsA
Ribose-phosphate pyrophosphokinase PrsA; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.938
nadR
Ribose phosphate pyrophosphokinase NadR; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 0.937
deoC
Deoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
  
 
 0.917
pgm
Phosphoglucomutase alpha-D-glucose phosphate-specific Pgm.
   
 0.912
deoB
Phosphopentomutase DeoB; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
   
 
 0.901
fba
Fructose-bisphosphate aldolase class II Calvin cycle subtype Fba; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
  
 0.862
pgl
6-phosphogluconolactonase Pgl; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
  
  
 0.778
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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