STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rihAPyrimidine-specific ribonucleoside hydrolase RihA; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. (318 aa)    
Predicted Functional Partners:
rbsK
Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.956
cpdB
Bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3`-nucleotidase CpdB; Belongs to the 5'-nucleotidase family.
 
    0.604
hprT
Hypoxanthine phosphoribosyltransferase HprT; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.582
hemN
Coproporphyrinogen III oxidase oxygen-independent HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.496
SO_0812
Uncharacterized protein.
       0.491
SO_0813
RCC1/BLIP-II superfamily lipoprotein.
       0.491
fliG
Flagellar motor switching and energizing component FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
    
   0.491
flaG
Uncharacterized flagella locus protein FlaG.
    
   0.491
polA
DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.479
purT
Phosphoribosylglycinamide formyltransferase 2 PurT; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
   
    0.466
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.