close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macAABC-type macrolide export systemMFP component MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (405 aa)    
Predicted Functional Partners:
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 0.999
macC
ABC-type macrolide export system secretin component MacC.
 0.997
tolC
Global secretion system secretin TolC.
  
 0.850
SO_3690
ABC-type macrolide family export system permease component 1.
 
 
 0.849
SO_4015
HAE1 family effllux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.813
SO_3691
ABC-type macrolide family export system permease component 2.
 
 
 0.793
SO_1925
RND superfamily efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
  0.746
vmeB
Proton-coupled multidrug efflux pump permease component VmeB.
   0.743
mexF
HAE1 family efflux pump permease component MexF.
 
 0.728
SO_4090
ABC-type efflux system secretin component.
  
 0.713
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.