STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SO_0946RND superfamily efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (400 aa)    
Predicted Functional Partners:
SO_0945
RND superfamily efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.971
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.909
tolC
Global secretion system secretin TolC.
  
 0.721
SO_4090
ABC-type efflux system secretin component.
  
 0.713
aggA
Type I protein secretion system secretin component AggA.
  
 0.704
SO_3278
RND superfamily efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
  0.697
exbB
TonB2 energy transduction system inner membrane component ExbB.
  
     0.686
ttpC
TonB2 energy transduction system inner membrane component TtpC.
  
     0.670
tonB2
TonB2 mediated energy transduction system energy transducer component TonB2; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
   
 0.613
SO_1925
RND superfamily efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
  0.613
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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