STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahpCAlkyl hydroperoxide reductase peroxiredoxin component AhpC; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (189 aa)    
Predicted Functional Partners:
ahpF
Alkyl hydroperoxide reductase flavoprotein component AhpF.
 
  
 0.990
katB
Catalase HPII KatB; Belongs to the catalase family.
  
 
 0.924
trxB
Thioredoxin reductase TrxB.
  
 
 0.921
katG
Bifunctional catalase/peroxidase HPI KatG; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
  
  
 0.746
SO_4640
Antioxidant AhpC/Tsa family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.706
katG-2
Bifunctional catalase/peroxidase HPI KatG; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
  
  
 0.698
fur
Transcriptional repressor of iron homeostasis Fur; Belongs to the Fur family.
  
  
 0.675
SO_1563
Cytoplasmic glutathione peroxidase.
   
 
 0.669
oxyR
Transcriptional regulator of oxidative stress OxyR; Belongs to the LysR transcriptional regulatory family.
 
  
 0.663
dpsA
DNA-binding ferritin-like protein (oxidative damage protectant) DpsA; Belongs to the Dps family.
  
  
 0.650
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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