STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhAFermentative lactate dehydrogenase NADH dependent LdhA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)    
Predicted Functional Partners:
pflB
Pyruvate formate-lyase PflB.
   
 
 0.981
dld
Respiratory FAD-dependent D-lactate dehydrogenase Dld.
   
 0.955
pykA
Pyruvate kinase II PykA; Belongs to the pyruvate kinase family.
  
 0.941
ppsA
Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.915
agxT
Serine-pyruvate aminotransferase AgxT.
  
 
 0.914
gloB
Hydroxyacylglutathione hydrolase GloB; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
 
 0.906
SO_3054
Metallo-beta-lactamase family protein.
  
 
 0.906
sfcA
NAD-dependent malate dehydrogenase (oxaloacetate-decarboxylating) SfcA; Belongs to the malic enzymes family.
    
 0.906
maeB
NADP-dependent malate dehydrogenase (oxaloacetate-decarboxylating) MaeB.
    
 0.906
aceE
Pyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.904
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.