| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| def-2 | fumB | SO_1062 | SO_2222 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.840 |
| def-2 | ilvD | SO_1062 | SO_4345 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. | 0.816 |
| def-2 | rplI | SO_1062 | SO_3927 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 0.812 |
| def-2 | rplM | SO_1062 | SO_3940 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L13 RplM; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.799 |
| def-2 | rplQ | SO_1062 | SO_0257 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L17 RplQ. | 0.823 |
| def-2 | rplT | SO_1062 | SO_2302 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L20 RplT; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.820 |
| def-2 | rplU | SO_1062 | SO_3652 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.813 |
| def-2 | rplV | SO_1062 | SO_0236 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L22 RplV; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.830 |
| def-2 | rpmA | SO_1062 | SO_3651 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L27 RpmA; Belongs to the bacterial ribosomal protein bL27 family. | 0.831 |
| def-2 | rpsO | SO_1062 | SO_1207 | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 30S ribosomal protein S15 RpsO; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.803 |
| fumB | def-2 | SO_2222 | SO_1062 | Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.840 |
| fumB | ilvD | SO_2222 | SO_4345 | Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. | 0.816 |
| ilvD | def-2 | SO_4345 | SO_1062 | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.816 |
| ilvD | fumB | SO_4345 | SO_2222 | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. | Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.816 |
| rplI | def-2 | SO_3927 | SO_1062 | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.812 |
| rplI | rplM | SO_3927 | SO_3940 | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 50S ribosomal protein L13 RplM; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.998 |
| rplI | rplQ | SO_3927 | SO_0257 | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 50S ribosomal protein L17 RplQ. | 0.998 |
| rplI | rplT | SO_3927 | SO_2302 | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 50S ribosomal protein L20 RplT; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.997 |
| rplI | rplU | SO_3927 | SO_3652 | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.996 |
| rplI | rplV | SO_3927 | SO_0236 | 50S ribosomal protein L9 RplI; Binds to the 23S rRNA. | 50S ribosomal protein L22 RplV; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.997 |
