STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brf2Bacterioferritin subunit 2 Bfr2; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (157 aa)    
Predicted Functional Partners:
brf1
Bacterioferritin subunit 1 Bfr1; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
 
 
 
0.988
hemH2
Ferrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
   
 
 0.912
hemH
Ferrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.909
bfd
Bacterioferritin-associated ferredoxin Bfd.
 
 
 0.858
dpsA
DNA-binding ferritin-like protein (oxidative damage protectant) DpsA; Belongs to the Dps family.
   
  
 0.738
SO_1977
Inner membrane of unknown function DUF307.
      
 0.608
SO_2118
Chemotaxis locus anti-sigma factor antagonist.
   
  
 0.593
SO_2319
Chemotaxis locus antisigma factor antogonist.
   
  
 0.593
acnD
2-methyl citrate dehydratase Fe-S dependent AcnD; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle II (propionate degradation route). In vivo under anaerobic conditions, AcnD catalyzes the stereospecific dehydration of (2S,3S)-methylcitrate (2-MC) to yield the trans isomer of 2-methyl-aconitate (2-MCA). AcnD can also accept citrate and cis- aconitate, but with a lower efficiency. 2-methylisocitrate and isocitrate are not substrates.
   
  
 0.568
SO_0202
Predicted membrane protein.
   
  
 0.560
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.