| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_1120 | guaA | SO_1120 | SO_3292 | Hypoxanthine/guanine permease AzgA family. | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | 0.426 |
| SO_1120 | proA | SO_1120 | SO_1122 | Hypoxanthine/guanine permease AzgA family. | Gamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.460 |
| SO_1120 | proB | SO_1120 | SO_1121 | Hypoxanthine/guanine permease AzgA family. | Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.482 |
| SO_1120 | purC | SO_1120 | SO_4066 | Hypoxanthine/guanine permease AzgA family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. | 0.428 |
| SO_1120 | purD | SO_1120 | SO_0441 | Hypoxanthine/guanine permease AzgA family. | Phosphoribosylamine-glycine ligase PurD; Belongs to the GARS family. | 0.459 |
| SO_1120 | purE | SO_1120 | SO_3554 | Hypoxanthine/guanine permease AzgA family. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.536 |
| SO_1120 | purK | SO_1120 | SO_3555 | Hypoxanthine/guanine permease AzgA family. | Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.528 |
| SO_1120 | purL | SO_1120 | SO_3287 | Hypoxanthine/guanine permease AzgA family. | Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.870 |
| SO_1120 | purM | SO_1120 | SO_2760 | Hypoxanthine/guanine permease AzgA family. | Phosphoribosylformylglycinamidine cyclo-ligase PurM. | 0.428 |
| SO_1120 | uraA | SO_1120 | SO_2879 | Hypoxanthine/guanine permease AzgA family. | N-acetylglucosamine/uracil transporter UraA. | 0.552 |
| guaA | SO_1120 | SO_3292 | SO_1120 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine/guanine permease AzgA family. | 0.426 |
| guaA | proA | SO_3292 | SO_1122 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Gamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.654 |
| guaA | proB | SO_3292 | SO_1121 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.577 |
| guaA | purC | SO_3292 | SO_4066 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. | 0.789 |
| guaA | purD | SO_3292 | SO_0441 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine-glycine ligase PurD; Belongs to the GARS family. | 0.939 |
| guaA | purE | SO_3292 | SO_3554 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.744 |
| guaA | purK | SO_3292 | SO_3555 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.751 |
| guaA | purL | SO_3292 | SO_3287 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.990 |
| guaA | purM | SO_3292 | SO_2760 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine cyclo-ligase PurM. | 0.806 |
| guaA | uraA | SO_3292 | SO_2879 | GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP. | N-acetylglucosamine/uracil transporter UraA. | 0.679 |