Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpiARibose 5-phosphate isomerase RpiA; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase Rpe; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.990
deoB
Phosphopentomutase DeoB; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
  
 
 0.971
rbsK
Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.970
tkt
Transketolase Tkt; Belongs to the transketolase family.
 
 
 0.966
gnd
6-phosphogluconate dehydrogenase decarboxylating Gnd; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 
 0.938
pgm
Phosphoglucomutase alpha-D-glucose phosphate-specific Pgm.
  
 
 0.921
nadR
Ribose phosphate pyrophosphokinase NadR; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 
 0.914
prsA
Ribose-phosphate pyrophosphokinase PrsA; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.914
SO_0878
Phosphoribulokinase.
     
 0.911
e4pd
D-erythrose-4-phosphate dehydrogenase E4pd; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.
   
 
 0.816
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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