| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_1292 | folB | SO_1292 | SO_1291 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.996 |
| SO_1292 | folC | SO_1292 | SO_3067 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | 0.563 |
| SO_1292 | folE | SO_1292 | SO_4254 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | GTP cyclohydrolase I FolE. | 0.919 |
| SO_1292 | folK | SO_1292 | SO_0871 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. | 0.923 |
| SO_1292 | folP | SO_1292 | SO_1198 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
| SO_1292 | ribD | SO_1292 | SO_3469 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.651 |
| SO_1292 | uppP | SO_1292 | SO_1293 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | Undecaprenol diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.749 |
| folB | SO_1292 | SO_1291 | SO_1292 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | 0.996 |
| folB | folC | SO_1291 | SO_3067 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | 0.698 |
| folB | folE | SO_1291 | SO_4254 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I FolE. | 0.939 |
| folB | folK | SO_1291 | SO_0871 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. | 0.991 |
| folB | folM | SO_1291 | SO_0772 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydrofolate reductase FolM. | 0.904 |
| folB | folP | SO_1291 | SO_1198 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.994 |
| folB | phoA | SO_1291 | SO_0830 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Periplasmic alkaline phosphatase PhoA; Belongs to the alkaline phosphatase family. | 0.902 |
| folB | phoD | SO_1291 | SO_0806 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Ca(2+)-dependent phospholipase D PhoD. | 0.904 |
| folB | ribD | SO_1291 | SO_3469 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.639 |
| folB | uppP | SO_1291 | SO_1293 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Undecaprenol diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.637 |
| folC | SO_1292 | SO_3067 | SO_1292 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK-like protein. | 0.563 |
| folC | folB | SO_3067 | SO_1291 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.698 |
| folC | folE | SO_3067 | SO_4254 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I FolE. | 0.803 |