STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Cooccurrence
Coexpression
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[Homology]
Score
ptsPPhosphotransferase system (PTS) enzyme I PtsP; Belongs to the PEP-utilizing enzyme family. (744 aa)    
Predicted Functional Partners:
ptsO
Phosphotransferase system (PTS) phosphohisitinoprotein-hexose phosphotransferase comonent PtsO.
  
 
 0.997
crr
Phosphotransferase system (PTS) glucose-specific IIA component Crr.
 
   
 0.955
ptsN
Phosphotransferase system (PTS) sugar-specific IIA component PtsN.
  
   
 0.857
rppH
RNA pyrophosphohydrolase RppH; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
    0.819
ptsH
Phosphotransferase system (PTS) phosphocarrier protein HPr PtsH.
  
 
 
 0.752
SO_1333
4-toluene sulfonate uptake permease family protein.
  
    0.701
thyA
Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.649
lgt
Prolipoprotein diacylglyceryl transferase Lgt; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.622
SO_0859
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
   
 
 0.518
ptsG
Phosphotransferase system (PTS) glucose-specific IIBC component PtsG.
 
   
 0.493
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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