STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseAsigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...] (207 aa)    
Predicted Functional Partners:
rseB
Sigma E factor regulatory protein RseB.
 
 0.999
rpoE
RNA polymerase sigma factor 24 RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.995
SO_3551
RNA polymerase sigma-70 factor ECF subfamily.
  
 
 0.957
rseC
Sigma E factor positive regulatory protein RseC.
 
  
 0.937
SO_3840
RNA polymerase sigma-70 factor ECF subfamily.
  
 
 0.923
SO_1986
RNA polymerase sigma factor ECF family 11; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.920
degS
Serine protease DegS.
  
 
 0.918
degQ
Periplasmic serine protease DegQ; Belongs to the peptidase S1C family.
  
 
 0.898
SO_3096
RNA polymerase sigma factor ECF family 28; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.897
nlpI
Globular tetratricopeptide repeat containing lipoprotein NlpI; May be involved in cell division.
  
   
 0.842
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.