STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
rseBSigma E factor regulatory protein RseB. (310 aa)    
Predicted Functional Partners:
rseA
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
 
 0.999
rseC
Sigma E factor positive regulatory protein RseC.
 
  
 0.999
rpoE
RNA polymerase sigma factor 24 RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
 
 0.982
SO_3840
RNA polymerase sigma-70 factor ECF subfamily.
 
 
 0.870
degS
Serine protease DegS.
  
  
 0.785
SO_1986
RNA polymerase sigma factor ECF family 11; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.776
degQ
Periplasmic serine protease DegQ; Belongs to the peptidase S1C family.
  
  
 0.774
SO_2562
SAM-dependent methyltransferase type 11.
  
     0.683
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
    0.600
lepA
Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.576
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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