| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argD | aroF | SO_0617 | SO_1361 | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.517 |
| argD | ilvI | SO_0617 | SO_2279 | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Acetolactate synthase III large subunit IlvI. | 0.733 |
| argD | lysC | SO_0617 | SO_3986 | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Lysine-sensitive aspartokinase III LysC; Belongs to the aspartokinase family. | 0.559 |
| argD | pheA | SO_0617 | SO_1367 | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Multifunctional chorismate mutase P/prephenate dehydratase/DAHP synthetase PheA. | 0.517 |
| argD | tyrA | SO_0617 | SO_1362 | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. | 0.515 |
| argD | wbnI | SO_0617 | SO_3180 | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Glycosyl transferase family 2 WbnI. | 0.740 |
| aroB | aroF | SO_0287 | SO_1361 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.961 |
| aroB | aroG | SO_0287 | SO_0756 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.915 |
| aroB | aroH | SO_0287 | SO_2646 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Phospho-2-dehydro-3-deoxyheptonate aldolase trp-sensitive AroH; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.975 |
| aroB | pheA | SO_0287 | SO_1367 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Multifunctional chorismate mutase P/prephenate dehydratase/DAHP synthetase PheA. | 0.987 |
| aroB | tyrA | SO_0287 | SO_1362 | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. | 0.944 |
| aroF | argD | SO_1361 | SO_0617 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.517 |
| aroF | aroB | SO_1361 | SO_0287 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.961 |
| aroF | aroG | SO_1361 | SO_0756 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.916 |
| aroF | aroH | SO_1361 | SO_2646 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Phospho-2-dehydro-3-deoxyheptonate aldolase trp-sensitive AroH; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.909 |
| aroF | hisG | SO_1361 | SO_2074 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | ATP phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.621 |
| aroF | ilvI | SO_1361 | SO_2279 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Acetolactate synthase III large subunit IlvI. | 0.782 |
| aroF | lysC | SO_1361 | SO_3986 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Lysine-sensitive aspartokinase III LysC; Belongs to the aspartokinase family. | 0.574 |
| aroF | pheA | SO_1361 | SO_1367 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Multifunctional chorismate mutase P/prephenate dehydratase/DAHP synthetase PheA. | 0.835 |
| aroF | tyrA | SO_1361 | SO_1362 | Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. | 0.925 |