| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0859 | SO_1416 | SO_0859 | SO_1416 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator LuxR family. | 0.688 |
| SO_0859 | SO_1417 | SO_0859 | SO_1417 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase. | 0.779 |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.991 |
| SO_0859 | cheR | SO_0859 | SO_2124 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system MCP methyltransferase CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. | 0.556 |
| SO_0859 | cheR-3 | SO_0859 | SO_3251 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system MCP methyltransferase CheR. | 0.556 |
| SO_0859 | prlS | SO_0859 | SO_2742 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS. | 0.986 |
| SO_0859 | rcsB | SO_0859 | SO_4444 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two-component system, NarL family, captular synthesis response regulator RcsB; Two component signal transduction system response regulator of capsule flagella and curli biosynthesis RcsB. | 0.871 |
| SO_0859 | torS | SO_0859 | SO_1230 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.989 |
| SO_0859 | ttrS | SO_0859 | SO_4155 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. | 0.683 |
| SO_1416 | SO_0859 | SO_1416 | SO_0859 | Two component signal transduction system response regulator LuxR family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.688 |
| SO_1416 | SO_1417 | SO_1416 | SO_1417 | Two component signal transduction system response regulator LuxR family. | Two component signal transduction system histidine kinase. | 0.964 |
| SO_1416 | SO_4002 | SO_1416 | SO_4002 | Two component signal transduction system response regulator LuxR family. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.651 |
| SO_1416 | barA | SO_1416 | SO_3457 | Two component signal transduction system response regulator LuxR family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.595 |
| SO_1416 | cheR | SO_1416 | SO_2124 | Two component signal transduction system response regulator LuxR family. | Chemotaxis signal transduction system MCP methyltransferase CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. | 0.535 |
| SO_1416 | cheR-3 | SO_1416 | SO_3251 | Two component signal transduction system response regulator LuxR family. | Chemotaxis signal transduction system MCP methyltransferase CheR. | 0.857 |
| SO_1416 | prlS | SO_1416 | SO_2742 | Two component signal transduction system response regulator LuxR family. | Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS. | 0.669 |
| SO_1416 | rcsB | SO_1416 | SO_4444 | Two component signal transduction system response regulator LuxR family. | Two-component system, NarL family, captular synthesis response regulator RcsB; Two component signal transduction system response regulator of capsule flagella and curli biosynthesis RcsB. | 0.523 |
| SO_1416 | torS | SO_1416 | SO_1230 | Two component signal transduction system response regulator LuxR family. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.636 |
| SO_1416 | ttrS | SO_1416 | SO_4155 | Two component signal transduction system response regulator LuxR family. | Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. | 0.852 |