Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ifcAPeriplasmic tetraheme flavocytochrome IfcA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (589 aa)    
Predicted Functional Partners:
nuoCD
NADH-ubiquinone oxidoreductase subunit CD NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.927
sye4
NAD(P)H:flavin oxidoreductase Sye4.
 
  
 0.912
SO_4506
Iron-sulfur cluster-binding protein.
  
 
 0.890
sye2
NAD(P)H:flavin oxidoreductase Sye2.
    
 0.886
fumB
Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.843
sdhB
Succinate dehydrogenase iron-sulfur protein SdhB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.814
frdB
Quinol:fumarate reductase FeS subunit FrdB.
 
 0.807
sdhC
Succinate dehydrogenase cytochrome b556 subunit SdhC.
  
 0.753
sdhD
Succinate dehydrogenase membrane anchor subunit SdhD; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.753
frdC
Quinol:fumarate reductase menaquinol-oxidizing subunit FrdC.
  
 0.739
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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