Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SO_1551Diguanylate cyclase. (518 aa)    
Predicted Functional Partners:
SO_4323
Bifunctional diguanylate cyclase/phosphodiesterase LasD-like protein.
 
  
 0.888
bpfA
Biofilm-promoting protein BpfA.
   
  
 0.822
SO_4003
Metal dependent phosphohydrolase with response regulator receiver modulation.
 
    0.808
mshH
Signalling protein with GGDEF and EAL domains MshH.
  
  
 0.807
SO_2498
Bifunctional diguanylate cyclase/phosphodiesterase with GAF and PAS sensory domains.
 
  
 0.791
SO_1255
Bifunctional diguanylate cyclase/phosphodiesterase.
  
   0.789
SO_2507
Bifunctional diguanylate cyclase/phosphodiesterase.
  
    0.785
SO_4145
Signalling protein with EAL and C2 domains.
  
    0.776
SO_4734
Bifunctional diguanylate cyclase/phosphodiesterase with PAS sensory domain.
 
 
 0.776
SO_2520
Signalling protein with GGDEF domain.
  
     0.774
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (20%) [HD]