| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_1227 | rdgC | SO_1227 | SO_1556 | c-di-GMP-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.731 |
| apaH | mutT | SO_3641 | SO_0410 | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | 0.652 |
| apaH | polA | SO_3641 | SO_4669 | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.672 |
| apaH | rdgC | SO_3641 | SO_1556 | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.743 |
| apaH | rnhA | SO_3641 | SO_2560 | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Ribonuclease HI RnhA; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.744 |
| apaH | yebG | SO_3641 | SO_2604 | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | UV induced SOS regulon protein YebG. | 0.715 |
| apaH | yqcC | SO_3641 | SO_1619 | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | tRNA pseudouridine synthase C-associated protein of unknown function DUF446 YqcC. | 0.773 |
| glyP | rdgC | SO_0858 | SO_1556 | Na(+)-linked D-alanine glycine transporter GlyP. | Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.701 |
| mutT | apaH | SO_0410 | SO_3641 | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.652 |
| mutT | polA | SO_0410 | SO_4669 | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.671 |
| mutT | rdgC | SO_0410 | SO_1556 | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.653 |
| mutT | rnhA | SO_0410 | SO_2560 | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | Ribonuclease HI RnhA; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.617 |
| mutT | yebG | SO_0410 | SO_2604 | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | UV induced SOS regulon protein YebG. | 0.658 |
| mutT | yqcC | SO_0410 | SO_1619 | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | tRNA pseudouridine synthase C-associated protein of unknown function DUF446 YqcC. | 0.709 |
| polA | apaH | SO_4669 | SO_3641 | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.672 |
| polA | mutT | SO_4669 | SO_0410 | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 7,8-dihydro-8-oxoguanine-triphosphatase MutT. | 0.671 |
| polA | rdgC | SO_4669 | SO_1556 | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.569 |
| polA | rnhA | SO_4669 | SO_2560 | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Ribonuclease HI RnhA; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.748 |
| polA | rpoA | SO_4669 | SO_0256 | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.405 |
| polA | yebG | SO_4669 | SO_2604 | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | UV induced SOS regulon protein YebG. | 0.454 |