| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| barA | csrA | SO_3457 | SO_3426 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | 0.934 |
| barA | rsmB-2 | SO_3457 | SO_1575 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.819 |
| barA | rsmC | SO_3457 | SO_0828 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 16S rRNA (guanine1207-N2)-methyltransferase RsmC; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | 0.477 |
| barA | uvrY | SO_3457 | SO_1860 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | Two component signal transduction system response regulator UvrY. | 0.999 |
| csrA | barA | SO_3426 | SO_3457 | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.934 |
| csrA | rsmB-2 | SO_3426 | SO_1575 | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.740 |
| csrA | uvrY | SO_3426 | SO_1860 | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | Two component signal transduction system response regulator UvrY. | 0.891 |
| rbgA | rplJ | SO_2590 | SO_0222 | 50s ribosomal subunit maturation GTPase RbgA; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.931 |
| rbgA | rrmJ | SO_2590 | SO_1196 | 50s ribosomal subunit maturation GTPase RbgA; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 23S rRNA (uridine2552-2'-O)-methyltransferase RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.944 |
| rbgA | rsmB-2 | SO_2590 | SO_1575 | 50s ribosomal subunit maturation GTPase RbgA; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.789 |
| rffG | rsmB-2 | SO_3167 | SO_1575 | dTDP-glucose-4,6-dehydratase RffG; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.729 |
| rffG | sirB | SO_3167 | SO_0480 | dTDP-glucose-4,6-dehydratase RffG; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | Sulfurtransferase SirB. | 0.920 |
| rplJ | rbgA | SO_0222 | SO_2590 | 50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 50s ribosomal subunit maturation GTPase RbgA; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.931 |
| rplJ | rrmJ | SO_0222 | SO_1196 | 50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 23S rRNA (uridine2552-2'-O)-methyltransferase RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.895 |
| rplJ | rsmB-2 | SO_0222 | SO_1575 | 50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.686 |
| rrmJ | rbgA | SO_1196 | SO_2590 | 23S rRNA (uridine2552-2'-O)-methyltransferase RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 50s ribosomal subunit maturation GTPase RbgA; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.944 |
| rrmJ | rplJ | SO_1196 | SO_0222 | 23S rRNA (uridine2552-2'-O)-methyltransferase RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.895 |
| rrmJ | rsmB-2 | SO_1196 | SO_1575 | 23S rRNA (uridine2552-2'-O)-methyltransferase RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.742 |
| rsmB-2 | barA | SO_1575 | SO_3457 | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.819 |
| rsmB-2 | csrA | SO_1575 | SO_3426 | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | 0.740 |