STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfaAOmega-3 polyunsaturated fatty acid synthase subunit PfaA. (2531 aa)    
Predicted Functional Partners:
nuoCD
NADH-ubiquinone oxidoreductase subunit CD NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.998
pfaD
Omega-3 polyunsaturated fatty acid synthase subunit PfaD.
 
 0.998
fabD
Malonyl CoA-acyl carrier protein transacylase FabD.
 
0.997
pfaB
Omega-3 polyunsaturated fatty acid synthase PfaB.
 
  
 0.995
pfaE
4'-phosphopantetheinyl transferase PfaE; Belongs to the P-Pant transferase superfamily.
 
 0.995
pfaC
Multi-domain beta-ketoacyl synthase PfaC; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
0.972
oleC
Polyolefin biosynthetic pathway AMP transfer protein OleC; Involved in olefin biosynthesis. Catalyzes the conversion of 2-alkyl-3-hydroxyalkanoic acids to beta-lactones in the presence of ATP (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.
 
 0.958
oleA
Polyolefin biosynthetic pathway thiolase OleA; Involved in olefin biosynthesis. Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28- hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.
 
  
 0.949
oleB
Polyolefin biosynthetic pathway thioesterase OleB; Involved in olefin biosynthesis. Catalyzes the elimination of carbon dioxide from beta-lactones to form the final olefin product (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.
 
 
 0.924
SO_1256
acyl-CoA thioester hydrolase, YbgC/YbaW family.
 
 
 0.922
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.