| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_3560 | SO_3848 | SO_3560 | SO_3848 | Predicted non-catalytic member of peptidase subfamily M16B. | Cytoplasmic protein of unknown function. | 0.970 |
| SO_3560 | rseP | SO_3560 | SO_1636 | Predicted non-catalytic member of peptidase subfamily M16B. | RseA degrading zinc metalloprotease RseP. | 0.971 |
| SO_3848 | SO_3560 | SO_3848 | SO_3560 | Cytoplasmic protein of unknown function. | Predicted non-catalytic member of peptidase subfamily M16B. | 0.970 |
| SO_3848 | SO_4022 | SO_3848 | SO_4022 | Cytoplasmic protein of unknown function. | Periplasmic peptidase family M16B. | 0.970 |
| SO_3848 | rseP | SO_3848 | SO_1636 | Cytoplasmic protein of unknown function. | RseA degrading zinc metalloprotease RseP. | 0.950 |
| SO_4022 | SO_3848 | SO_4022 | SO_3848 | Periplasmic peptidase family M16B. | Cytoplasmic protein of unknown function. | 0.970 |
| SO_4022 | rseP | SO_4022 | SO_1636 | Periplasmic peptidase family M16B. | RseA degrading zinc metalloprotease RseP. | 0.969 |
| bamA | cdsA | SO_1637 | SO_1634 | Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Phosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. | 0.748 |
| bamA | dxr | SO_1637 | SO_1635 | Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.682 |
| bamA | rseP | SO_1637 | SO_1636 | Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | RseA degrading zinc metalloprotease RseP. | 0.973 |
| bamA | skp | SO_1637 | SO_1638 | Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Periplasmic chaperone for outer membrane proteins Skp; Belongs to the skp family. | 0.967 |
| bamA | uppS | SO_1637 | SO_1633 | Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Undecaprenyl diphosphate synthase UppS; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.680 |
| cdsA | bamA | SO_1634 | SO_1637 | Phosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. | Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.748 |
| cdsA | dxr | SO_1634 | SO_1635 | Phosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.950 |
| cdsA | rseP | SO_1634 | SO_1636 | Phosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. | RseA degrading zinc metalloprotease RseP. | 0.894 |
| cdsA | skp | SO_1634 | SO_1638 | Phosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. | Periplasmic chaperone for outer membrane proteins Skp; Belongs to the skp family. | 0.553 |
| cdsA | uppS | SO_1634 | SO_1633 | Phosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. | Undecaprenyl diphosphate synthase UppS; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.994 |
| degS | rseA | SO_3943 | SO_1343 | Serine protease DegS. | sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...] | 0.967 |
| degS | rseP | SO_3943 | SO_1636 | Serine protease DegS. | RseA degrading zinc metalloprotease RseP. | 0.884 |
| degS | skp | SO_3943 | SO_1638 | Serine protease DegS. | Periplasmic chaperone for outer membrane proteins Skp; Belongs to the skp family. | 0.687 |