Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ivdBMethylmalonate-semialdehyde dehydrogenase IvdB. (499 aa)    
Predicted Functional Partners:
ivdA
3-ketoacyl-CoA thiolase IvdA; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.986
ivdF
3-hydroxyisobutyrate dehydrogenase IvdF; Belongs to the HIBADH-related family.
 
 
 0.980
prpC
2-methylcitrate synthase PrpC; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle II (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Catalyzes the condensation of oxaloacetate with acetyl-CoA (By similarity).
  
 0.939
puuE
GABA aminotransferase PLP-dependent PuuE; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.928
pta
Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.926
aptA
Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.924
ivdE
3-hydroxyisobutyryl-CoA hydrolase IvdE.
 
 0.921
fadA
Aerobic fatty oxidation complex 3-ketoacyl-CoA thiolase beta subunit FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
    
 0.917
bkdB
3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB.
   
 
 0.916
fadI
Anaerobic fatty oxidation complex beta subunit FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
    
 0.916
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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