STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oleAPolyolefin biosynthetic pathway thiolase OleA; Involved in olefin biosynthesis. Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28- hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature. (349 aa)    
Predicted Functional Partners:
accADCB
acetyl-CoA carboxylase multifunctional enzyme AccADCB.
 
  
 0.980
oleB
Polyolefin biosynthetic pathway thioesterase OleB; Involved in olefin biosynthesis. Catalyzes the elimination of carbon dioxide from beta-lactones to form the final olefin product (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.
  
 0.975
oleC
Polyolefin biosynthetic pathway AMP transfer protein OleC; Involved in olefin biosynthesis. Catalyzes the conversion of 2-alkyl-3-hydroxyalkanoic acids to beta-lactones in the presence of ATP (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.
  
 0.974
pfaC
Multi-domain beta-ketoacyl synthase PfaC; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.969
pfaA
Omega-3 polyunsaturated fatty acid synthase subunit PfaA.
 
  
 0.949
oleD
Polyolefin biosynthetic pathway dehydrogenase/isomerase OleD; Involved in olefin biosynthesis. Catalyzes the reversible stereospecific NADPH-dependent reduction of 2-alkyl-3- oxoalkanoic acids to 2-alkyl-3-hydroxyalkanoic acids (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28- hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.
 
  
 0.845
vmeA
Proton-coupled multidrug efflux pump MFP component VmeA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
   
  
 0.810
SO_4008
Putative recombination regulator protein DUF3584 family.
     
 0.803
fabD
Malonyl CoA-acyl carrier protein transacylase FabD.
 
  
 0.788
pfaB
Omega-3 polyunsaturated fatty acid synthase PfaB.
 
  
 0.771
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.