Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SO_1822TonB-dependent receptor. (936 aa)    
Predicted Functional Partners:
rfaH
Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family.
      
 0.798
SO_2583
Methyltransferase.
  
     0.739
SO_2198
Peptidase M28 family.
  
     0.697
SO_2766
Peptidase M28A family.
  
     0.693
SO_3539
Peptidase M28D family.
  
     0.678
tonB-3
TonB mediated energy transduction system energy transducer component TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.674
dpp4
Periplasmic dipeptidylpeptidase IV Dpp4.
  
     0.631
SO_3361
Protein of unknown function DUF885.
  
    0.595
tonB2
TonB2 mediated energy transduction system energy transducer component TonB2; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.591
SO_2715
Thiamine-regulated TonB-dependent receptor.
  
   
 0.582
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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