Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
liuRTranscriptional repressor of branched chain amino acid degradation LiuR. (134 aa)    
Predicted Functional Partners:
nrtR
Transcriptional repressor of nicotinamide riboside utilization NrtR.
      
 0.803
psrA
Transcriptional repressor of fatty acid degradation PsrA.
      
 0.803
liuE
3-hydroxymethylglutaryl-CoA lyase LiuE.
 
  
 0.746
tyrR
Sigma54-dependent transcriptional activator of amino acid degradation TyrR.
   
  
 0.707
liuD
methylcrotonyl-CoA carboxylase biotin-binding subunit LiuD.
  
 
 0.674
hexR
RpiR family transcriptional regulator, carbohydrate utilization regulator; 2-keto-3-deoxy-6-phosphogluconate-responsive transcriptional regulator of central carbohydrate metabolism HexR.
      
 0.664
nrdR
Transcriptional repressor of deoxyribonucleotide biosynthesis NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
   
  
 0.663
hmgR
Homogentisate-responsive transcriptional repressor of homogenetisate degradation HmgR; Belongs to the LysR transcriptional regulatory family.
      
 0.662
liuB
methylcrotonyl-CoA carboxylase carboxyl transferase subunit LiuB.
  
  
 0.635
fadR
Transcriptional regulator of fatty acid metabolism FadR; Multifunctional regulator of fatty acid metabolism.
  
  
 0.596
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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