| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0033 | SO_0119 | SO_0033 | SO_0119 | Peptidoglycan-binding protein. | Periplasmic protein of unknown function DUF1090. | 0.590 |
| SO_0033 | ybaY | SO_0033 | SO_1913 | Peptidoglycan-binding protein. | Putative chaperone for general secretion pathway YbaY. | 0.595 |
| SO_0119 | SO_0033 | SO_0119 | SO_0033 | Periplasmic protein of unknown function DUF1090. | Peptidoglycan-binding protein. | 0.590 |
| SO_0119 | ybaY | SO_0119 | SO_1913 | Periplasmic protein of unknown function DUF1090. | Putative chaperone for general secretion pathway YbaY. | 0.469 |
| SO_1911 | menA | SO_1911 | SO_1910 | Oxidoreductase short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.405 |
| SO_1911 | tesB | SO_1911 | SO_1912 | Oxidoreductase short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | acyl-CoA thioesterase II TesB. | 0.581 |
| SO_1911 | ybaY | SO_1911 | SO_1913 | Oxidoreductase short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Putative chaperone for general secretion pathway YbaY. | 0.498 |
| SO_3174 | menA | SO_3174 | SO_1910 | O-antigen biosynthesis glycosyl transferase family 4. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.739 |
| SO_3174 | menF | SO_3174 | SO_4713 | O-antigen biosynthesis glycosyl transferase family 4. | Menaquinone-specific isochorismate synthase MenF; Catalyzes the conversion of chorismate to isochorismate. | 0.565 |
| SO_3174 | ybaY | SO_3174 | SO_1913 | O-antigen biosynthesis glycosyl transferase family 4. | Putative chaperone for general secretion pathway YbaY. | 0.736 |
| menA | SO_1911 | SO_1910 | SO_1911 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Oxidoreductase short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.405 |
| menA | SO_3174 | SO_1910 | SO_3174 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | O-antigen biosynthesis glycosyl transferase family 4. | 0.739 |
| menA | menF | SO_1910 | SO_4713 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Menaquinone-specific isochorismate synthase MenF; Catalyzes the conversion of chorismate to isochorismate. | 0.720 |
| menA | ubiA | SO_1910 | SO_0468 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 4-hydroxybenzoate octaprenyltransferase UbiA; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.497 |
| menA | ybaY | SO_1910 | SO_1913 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Putative chaperone for general secretion pathway YbaY. | 0.799 |
| menF | SO_3174 | SO_4713 | SO_3174 | Menaquinone-specific isochorismate synthase MenF; Catalyzes the conversion of chorismate to isochorismate. | O-antigen biosynthesis glycosyl transferase family 4. | 0.565 |
| menF | menA | SO_4713 | SO_1910 | Menaquinone-specific isochorismate synthase MenF; Catalyzes the conversion of chorismate to isochorismate. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.720 |
| menF | ybaY | SO_4713 | SO_1913 | Menaquinone-specific isochorismate synthase MenF; Catalyzes the conversion of chorismate to isochorismate. | Putative chaperone for general secretion pathway YbaY. | 0.577 |
| parC | tpx | SO_3897 | SO_3341 | DNA topoisomerase IV A subunit ParC; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | Thiol peroxidase Tpx; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.431 |
| parC | ubiA | SO_3897 | SO_0468 | DNA topoisomerase IV A subunit ParC; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 4-hydroxybenzoate octaprenyltransferase UbiA; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.444 |